Model year guide

2006 Mercedes-benz cls500

Recalls, most-reported problems, crash-test ratings, fuel economy and what a 2006 Mercedes-benz cls500 is worth — from official NHTSA and EPA data. 1 on record.

2006 Mercedes-benz cls500 — representative photo
Representative photo

2006 Mercedes-benz cls500 at a glance

Safety recalls3
Combined16 mpg

Free: that car's specs and build sheet, model-year recall campaigns and a fair price.

2006 Mercedes-benz cls500 recalls 3

Visibility:sun/moon Roof Assembly NHTSA Campaign #24V874000 · manufacturer #2024120001/2/3 · 19/11/2024

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2001-2011 C-Class, CLK, E-Class, and CLS vehicles. Please see the recall report for a complete list of models and model years. The glass sunroof panel may not be properly secured and can detach.

Fix: Dealers will inspect and replace the sunroof panel as necessary, free of charge. Owner notification letters were mailed January 10, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of previous NHTSA recall number 22V-954. MBUSA's number for this recall …

Visibility:sun/moon Roof Assembly NHTSA Campaign #21V196000 · manufacturer #2021040012 · 19/03/2021

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2006-2007 C350, C230, C280, CLK350, E320CDI, E350 Wagon, E350, 2006 C55 AMG, CLK500, CLS500, CLS55 AMG, E500 Wagon, E500, E55 AMG, 2007 CLK550, CLS550, CLS63 AMG, E550, E63 AMG, and E63 Wagon AMG vehicles. The bonding between the glass panel and the sliding roof frame may deteriorate, possibly causing the glass panel to detach from the vehicle.

Fix: MBUSA will notify owners, and dealers will inspect the glass panel bonding and replace the sliding roof, as necessary, free of charge. Owner letters were mailed May 7, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of recall number 19V-918. MBUSA's nu…

Visibility:sun/moon Roof Assembly NHTSA Campaign #19V918000 · manufacturer #2020040011 · 20/12/2019

Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2001-2011 vehicles. The bonding between the glass panel and the sliding roof frame may deteriorate, possibly resulting in the glass panel detaching from the vehicle. For a full list of the affected models visit: https://static.nhtsa.gov/odi/rcl/2019/RMISC-19V918-4126.pdf

Fix: MBUSA will notify owners, and dealers will inspect the glass panel bonding and replace the sliding roof, as necessary, free of charge. The recall began July 10, 2020. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2020040011.

Source: U.S. NHTSA, checked 7 Oct 2026. A campaign covers the model year; to see whether a particular car still needs the repair, check its VIN on NHTSA.gov or ask a franchised dealer.

2006 Mercedes-benz cls500 MPG & running costs

Combined16 mpg
City14 mpg
Highway20 mpg
Est. annual fuel cost$5,150
EPA size classCompact Cars
TransmissionAutomatic 7-spd
Passenger volume93 cu ft
Cargo volume13 cu ft
5-yr fuel cost vs average new car$13,750 more

Source: U.S. EPA / DOE fueleconomy.gov.

Estimated 5-year cost to own

A rough guide to what running a 2006 Mercedes-benz cls500 costs over five years and 75,000 miles.

Fuel (5 yrs)$25,750
Fuel only$25,750
Per mile$0.34

How this is estimated: fuel is the U.S. EPA annual cost at 15,000 miles a year. There aren't enough comparable listings to estimate depreciation for this model, so it is left out. Not included: insurance, maintenance, repairs, taxes, registration and finance costs. Treat it as a comparison guide, not a quote.

2006 Mercedes-benz cls500 trims & engines on record

Trims
CLS550
Engines
5.0L 8-cyl 302 hp

2006 Mercedes-benz cls500 vehicles on record

2006 Mercedes-benz cls500 — frequently asked questions

Does the 2006 Mercedes-benz cls500 have any safety recalls?

NHTSA lists 3 recall campaigns for the 2006 Mercedes-benz cls500. Whether an individual car still needs a recall repair depends on its VIN — check it on NHTSA.gov or ask a franchised dealer. Recall repairs are free.

What gas mileage does the 2006 Mercedes-benz cls500 get?

The 2006 Mercedes-benz cls500 has a U.S. EPA estimate of 16 mpg combined (14 city / 20 highway).

Sources: NHTSA (recalls, complaints, crash tests), U.S. EPA (fuel economy). Vehicle data only — CarLogs never shows owner information.