2022 Lexus RX 350 problems, recalls, safety rating, MPG & value

Q: What gas mileage does the 2022 Lexus RX 350 get?

The 2022 Lexus RX 350 has a U.S. EPA estimate of 23 mpg combined (20 city / 27 highway).

2022 Lexus RX 350 at a glance

Safety recallsNone

Owner complaints39

Combined23 mpg

Free: that car's specs and build sheet, model-year recall campaigns and a fair price.

2022 Lexus RX 350 recalls 0

No NHTSA safety-recall campaigns are on record for the 2022 Lexus RX 350.

Source: U.S. NHTSA, checked 7 Oct 2026. A campaign covers the model year; to see whether a particular car still needs the repair, check its VIN on NHTSA.gov or ask a franchised dealer.

2022 Lexus RX 350 common problems

The most-reported problem areas across all 39 owner complaints filed with NHTSA — and what to check before you buy.

Electrical System

Test every electrical feature: windows, locks, infotainment, charging and all lights. Watch for flickering, dead accessories or warning lights.

Fuel/propulsion System

Check for fuel or battery warnings, hard starts and stalling. On a hybrid/EV, confirm charging and range behave normally.

Service Brakes

Brakes should feel firm and quiet — no grinding, pulsing or pulling. Check for an ABS light and uneven pad/rotor wear.

Power Train

Drive through every gear: watch for slipping, hard or delayed shifts, and shudder. Check for transmission/driveline leaks and noises.

Engine

Listen for knocks or ticking, check for leaks and blue/white exhaust smoke, and make sure it doesn't overheat. No check-engine light should be on.

Tires

Check tread depth, the DOT age date, and that all four tires match with even wear. Look for bulges or cracks.

2022 Lexus RX 350 MPG & running costs

Combined23 mpg

City20 mpg

Highway27 mpg

Est. annual fuel cost$2,900

EPA size classSmall Sport Utility Vehicle 2WD

TransmissionAutomatic (S8)

5-yr fuel cost vs average new car$2,500 more

Source: U.S. EPA / DOE fueleconomy.gov.

Estimated 5-year cost to own

A rough guide to what running a 2022 Lexus RX 350 costs over five years and 75,000 miles.

Fuel (5 yrs)$14,500

Fuel only$14,500

Per mile$0.19

How this is estimated: fuel is the U.S. EPA annual cost at 15,000 miles a year. There aren't enough comparable listings to estimate depreciation for this model, so it is left out. Not included: insurance, maintenance, repairs, taxes, registration and finance costs. Treat it as a comparison guide, not a quote.

2022 Lexus RX 350 vehicles on record

Other Lexus RX 350 model years

2022 Lexus RX 350 — frequently asked questions

Does the 2022 Lexus RX 350 have any safety recalls?

NHTSA lists no safety-recall campaigns for the 2022 Lexus RX 350. Whether an individual car still needs a recall repair depends on its VIN — check it on NHTSA.gov or ask a franchised dealer. Recall repairs are free.

What are the most common problems with the 2022 Lexus RX 350?

Across all 39 owner complaints filed with NHTSA, the most-reported problem areas are electrical system, fuel/propulsion system, service brakes.

What gas mileage does the 2022 Lexus RX 350 get?

The 2022 Lexus RX 350 has a U.S. EPA estimate of 23 mpg combined (20 city / 27 highway).

Sources: NHTSA (recalls, complaints, crash tests), U.S. EPA (fuel economy). Vehicle data only — CarLogs never shows owner information.