Model year guide

2021 Mercedes-benz E 450

Recalls, most-reported problems, crash-test ratings, fuel economy and what a 2021 Mercedes-benz E 450 is worth — from official NHTSA and EPA data. 18 on record.

2021 Mercedes-benz E 450 at a glance

Combined24–26 mpg

Free: that car's specs and build sheet, model-year recall campaigns and a fair price.

2021 Mercedes-benz E 450 MPG & running costs

Combined24–26 mpg
City23 mpg
Highway30 mpg
Est. annual fuel cost$3,267
EPA size classSubcompact Cars
TransmissionAutomatic 9-spd
Forced inductionTurbocharged
Engine start-stopYes
Passenger volume98 cu ft
Cargo volume35 cu ft
5-yr fuel cost vs average new car$4,333 more

Source: U.S. EPA / DOE fueleconomy.gov. The EPA lists 6 versions of this model year; combined is shown as a range and the other figures are averages.

Estimated 5-year cost to own

A rough guide to what running a 2021 Mercedes-benz E 450 costs over five years and 75,000 miles.

Fuel (5 yrs)$16,335
Fuel only$16,335
Per mile$0.22

How this is estimated: fuel is the U.S. EPA annual cost at 15,000 miles a year. There aren't enough comparable listings to estimate depreciation for this model, so it is left out. Not included: insurance, maintenance, repairs, taxes, registration and finance costs. Treat it as a comparison guide, not a quote.

2021 Mercedes-benz E 450 vehicles on record

Other Mercedes-benz E 450 model years

2021 Mercedes-benz E 450 — frequently asked questions

What gas mileage does the 2021 Mercedes-benz E 450 get?

The 2021 Mercedes-benz E 450 has U.S. EPA estimates of 24–26 mpg combined, depending on engine and trim (6 versions).

Sources: NHTSA (recalls, complaints, crash tests), U.S. EPA (fuel economy). Vehicle data only — CarLogs never shows owner information.