Model year guide

2021 Mercedes-benz GLS 450

Recalls, most-reported problems, crash-test ratings, fuel economy and what a 2021 Mercedes-benz GLS 450 is worth — from official NHTSA and EPA data. 77 on record.

2021 Mercedes-benz GLS 450 at a glance

Safety recalls12
Combined21 mpg

Free: that car's specs and build sheet, model-year recall campaigns and a fair price.

2021 Mercedes-benz GLS 450 recalls 12

Electrical System:wiring NHTSA Campaign #24V207000 · manufacturer #2024040002 · 15/03/2024

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2023-2024 GLE 350, 2020-2024 GLE 450, 2020-2023 GLS 580, GLE 580, 2019-2023 GLS 450, 2021-2023 Maybach GLS 600, AMG GLS 63, 2021-2024 AMG GLE 53, AMG GLE 53 Coupe, and AMG GLE 63 S vehicles. A 48-Volt ground connection under the passenger seat may not be secured properly, resulting in the ground connection overheating.

Fix: Dealers will inspect and tighten the 48-Volt ground connection as necessary, free of charge. Owner notification letters were mailed on May 3, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024040002.

Power Train:automatic Transmission:control Module:software NHTSA Campaign #24V118000 · 16/02/2024

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2023 GLE 450 and GLS 450 vehicles. The transmission may not fully downshift in certain conditions, causing the engine to stall.

Fix: Dealers will update the transmission control unit software, free of charge. Owner notification letters were mailed March 29, 2024. Owners may contact MBUSA customer service at 1-800-367-6372.

Fuel System, Gasoline:delivery:fuel Pump NHTSA Campaign #23V445000 · manufacturer #2023070012 · 26/06/2023

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.

Fix: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.

Visibility:defroster/defogger/hvac System NHTSA Campaign #23V177000 · manufacturer #2023030014 & 15 · 17/03/2023

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2021 GLE350, GLE450, GLS450, GLS580, 2021 AMG GLE53, AMG GLE63, Maybach GLS600, AMG GLS63, and 2020 GLE580 vehicles. The air conditioner drain hoses may have been incorrectly installed, causing water to drain into the passenger compartment.

Fix: Dealers will inspect and reinstall the air conditioner drain hoses, as necessary, free of charge. Owner notification letters were mailed April 28, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of recall numbers 21V-288 and 19V-587. MBUSA's numbers fo…

Seats:mid/rear Assembly NHTSA Campaign #22V732000 · manufacturer #2022100011 · 30/09/2022

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 AMG GLS63, 2020-2022 GLS450 and GLS580 vehicles. Due to a manufacturing error, the locks on the third-row seatbacks may fail in the event of a crash.

Fix: Dealers will inspect and replace the third-row seatback, as necessary, free of charge. Owner notification letters were mailed November 18, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022100011.

Structure:body NHTSA Campaign #22V680000 · manufacturer #2022090010 · 12/09/2022

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2022 GLE350, GLE450, GLS450, 2021-2022 AMG GLE53, 2020-2021 GLE580, GLS580, and 2021 GLE400e, AMG GLS63, AMG GLE63 S, and Maybach GLS600 vehicles. Due to a manufacturing error, the rear door window trim bars may detach.

Fix: Dealers will inspect and secure the rear window trim bars, as necessary, free of charge. Owner notification letters were mailed November 1, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022090010.

Communication: Auto Crash Notification NHTSA Campaign #22V365000 · manufacturer #See Recall Schedule · 20/05/2022

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling…

Fix: The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owne…

Electrical System:wiring:interior/under Dash NHTSA Campaign #22V231000 · manufacturer #2022040017 · 08/04/2022

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2022 GLE450, GLS450, 2021-2022 AMG GLE53, 2020-2021 GLE580, GLS580, 2021 AMG GLE63, Maybach GLS600 and AMG GLS63 vehicles. A ground cable bolt for the 48V ground connection under the front passenger seat may not be secured properly, which can cause the electrical cable to overheat.

Fix: Dealers will inspect and tighten the ground cable bolt, as necessary, free of charge. Owner notification letters were mailed July 8, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040017.

Visibility:glass, Side/rear NHTSA Campaign #21V832000 · manufacturer #2021110007 · 22/10/2021

Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 GLE 350, GLE 580, GLS 450, GLS 580, AMG GLE 53, AMG GLE 63 S, and AMG GLS 63 S vehicles. The rear window may be insufficiently bonded to the tailgate, which could allow the rear glass to detach.

Fix: Dealers will replace the rear window, free of charge. Owner notification letters were mailed December 8, 2021. Owners may contact MBUSA customer service at 1-800-367-6372.

Back Over Prevention: Sensing System: Camera NHTSA Campaign #21V354000 · manufacturer #2021050012 · 14/05/2021

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The MBUX multimedia system software may cause the display to remain black, or reboot after startup. This could result in the rearvi…

Fix: The multimedia system software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed beginning June 28, 2021. Owners may contact MBUSA customer service at 1-800-367-6373. MBUSA's number for this recall is 2021050012.

Communication: Auto Crash Notification NHTSA Campaign #21V058000 · manufacturer #2021020025 · 05/02/2021

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the…

Fix: MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.

Electrical System: Instrument Cluster/panel NHTSA Campaign #20V089000 · manufacturer #2020030019 · 14/02/2020

Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2020 CLA250, CLA250 4MATIC and CLA35 AMG 4MATIC, 2020-2021 GLE350, GLE350 4MATIC, GLE450 4MATIC, GLS450 4MATIC and GLS580 4MATIC and 2021 GLE53 AMG Coupe, GLE63S AMG 4MATIC, GLS63 AMG 4MATIC and Maybach GLS600 4MATIC vehicles. The instrument cluster software may deactivate the illumination of certain interior switches (switch bar, overhead control unit, steering w…

Fix: MBUSA will notify owners, and dealers will update the instrument cluster software, free of charge. The recall began March 31, 2020. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2020030019.

Source: U.S. NHTSA, checked 8 Oct 2026. A campaign covers the model year; to see whether a particular car still needs the repair, check its VIN on NHTSA.gov or ask a franchised dealer.

2021 Mercedes-benz GLS 450 MPG & running costs

Combined21 mpg
City20 mpg
Highway24 mpg
Est. annual fuel cost$3,900
EPA size classStandard Sport Utility Vehicle 4WD
TransmissionAutomatic 9-spd
Forced inductionTurbocharged
Engine start-stopYes
5-yr fuel cost vs average new car$7,500 more

Source: U.S. EPA / DOE fueleconomy.gov.

Estimated 5-year cost to own

A rough guide to what running a 2021 Mercedes-benz GLS 450 costs over five years and 75,000 miles.

Fuel (5 yrs)$19,500
Fuel only$19,500
Per mile$0.26

How this is estimated: fuel is the U.S. EPA annual cost at 15,000 miles a year. There aren't enough comparable listings to estimate depreciation for this model, so it is left out. Not included: insurance, maintenance, repairs, taxes, registration and finance costs. Treat it as a comparison guide, not a quote.

2021 Mercedes-benz GLS 450 vehicles on record

Other Mercedes-benz GLS 450 model years

2021 Mercedes-benz GLS 450 — frequently asked questions

Does the 2021 Mercedes-benz GLS 450 have any safety recalls?

NHTSA lists 12 recall campaigns for the 2021 Mercedes-benz GLS 450. Whether an individual car still needs a recall repair depends on its VIN — check it on NHTSA.gov or ask a franchised dealer. Recall repairs are free.

What gas mileage does the 2021 Mercedes-benz GLS 450 get?

The 2021 Mercedes-benz GLS 450 has a U.S. EPA estimate of 21 mpg combined (20 city / 24 highway).

Sources: NHTSA (recalls, complaints, crash tests), U.S. EPA (fuel economy). Vehicle data only — CarLogs never shows owner information.