2022 Mercedes-benz S 500 4MATIC
Recalls, most-reported problems, crash-test ratings, fuel economy and what a 2022 Mercedes-benz S 500 4MATIC is worth — from official NHTSA and EPA data. 1 on record.
2022 Mercedes-benz S 500 4MATIC at a glance
Included: that car's specs and build sheet, model-year recall campaigns and a fair price.
2022 Mercedes-benz S 500 4MATIC recalls 9
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022-2025 S 500 4MATIC, Maybach S 580 4MATIC, Maybach S 680 4MATIC, S 580 4MATIC, 2023-2025 S 580 E 4MATIC, and 2024-2025 AMG S 63 E Performance vehicles. The front brake hoses may rupture and leak brake fluid.
Fix: Dealers will replace the front brake hoses, free of charge. Owner notification letters are expected to be mailed November 27, 2026. Owners may contact MBUSA customer service at 1-800-367-6372. This recall expands previous NHTSA recall number 25V116. Vehicle Identification Numbers (VINs) involved in…
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 S 500, Maybach S 580 4MATIC, 2021-2023 S 580 4MATIC, 2022 S 680 4MATIC, and 2023 S 580e 4MATIC vehicles. The front brake hoses may rupture and leak brake fluid.
Fix: Dealers will replace the front brake hoses, free of charge. Owner notification letters were mailed April 25, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2025030007.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.
Fix: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024, August 9, 2024, October 1, 2024, and December 2, 2024. Owners may contact MBUSA cust…
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.
Fix: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.
Mercedes-Benz USA, LLC (MBUSA) is recalling one 2022 S 500 vehicle. The dashboard may be insufficiently attached, which can result in an improper front passenger air bag deployment in the event of a crash.
Fix: Dealers will replace a portion of the dashboard, free of charge. The owner notification letter was mailed January 20, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023010001.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 S580Z, S500V, and S580V vehicles. The sub frame weld for the thrust arm on the rear axle carrier may have been improperly welded, causing the thrust arm to break and detach.
Fix: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will inspect the sub frame weld on the rear axle carrier and replace the rear axle carrier as necessary, free of charge. Owner notification letters were mailed April 8, 2022. Owners may contact MBUSA custome…
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.
Fix: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 EQS450, S500, and S580 vehicles. The communication module software may restrict or disable the emergency call system (eCall).
Fix: The communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed February 23, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022010006.
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 S580, 2022 EQS450, EQS580, and S500 vehicles with an active and connected Mercedes me connect account. The MBUX infotainment system might allow activation of the television and internet display while driving, causing a distraction for the driver.
Fix: MBUSA has updated their computer server to correct the issue for most vehicles, free of charge. For vehicles that were not able to be updated remotely, dealers will provide the software update, free of charge. Owner notification letters were mailed January 25, 2022. Owners may contact MBUSA custome…
Source: U.S. NHTSA, checked 14 Oct 2026. A campaign covers the model year; to see whether a particular car still needs the repair, check its VIN on NHTSA.gov or ask a franchised dealer.
2022 Mercedes-benz S 500 4MATIC MPG & running costs
Source: U.S. EPA / DOE fueleconomy.gov.
Estimated 5-year cost to own
A rough guide to what running a 2022 Mercedes-benz S 500 4MATIC costs over five years and 75,000 miles.
How this is estimated: fuel is the U.S. EPA annual cost at 15,000 miles a year. There aren't enough comparable listings to estimate depreciation for this model, so it is left out. Not included: insurance, maintenance, repairs, taxes, registration and finance costs. Treat it as a comparison guide, not a quote.