Model year guide

2021 Mercedes-benz S 580

Recalls, most-reported problems, crash-test ratings, fuel economy and what a 2021 Mercedes-benz S 580 is worth — from official NHTSA and EPA data. 83 on record.

2021 Mercedes-benz S 580 at a glance

Safety recalls16
Combined19–20 mpg

Included: that car's specs and build sheet, model-year recall campaigns and a fair price.

2021 Mercedes-benz S 580 recalls 16

Service Brakes, Hydraulic:foundation Components NHTSA Campaign #25V116000 · manufacturer #2025030007 · 24/02/2025

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 S 500, Maybach S 580 4MATIC, 2021-2023 S 580 4MATIC, 2022 S 680 4MATIC, and 2023 S 580e 4MATIC vehicles. The front brake hoses may rupture and leak brake fluid.

Fix: Dealers will replace the front brake hoses, free of charge. Owner notification letters were mailed April 25, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2025030007.

Communication: Auto Crash Notification NHTSA Campaign #24V807000 · manufacturer #2024110002 · 25/10/2024

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 Maybach S 580 4MATIC, S 500 4MATIC, and S 580 4MATIC vehicles. The emergency call system may fail to place an automatic or manual call and may not provide the vehicle location as intended.

Fix: Dealers will update the communication module software, free of charge. Owner notification letters were mailed December 6, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024110002.

Engine And Engine Cooling:engine:engine Control Module (ecu/ecm):software NHTSA Campaign #24V704000 · manufacturer #2024100007 · 20/09/2024

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 S580, and Maybach S580 vehicles. In the event of a mechanical failure in the engine Camtronic system, the engine control unit (ECU) software may cause the engine to overheat or stall.

Fix: Dealers will update the ECU software, free of charge. Owner notification letters were mailed on November 15, 2024. Owner notification letters will be mailed in phases, on November 15, 2024, January 10, 2025, and February 21, 2025. Owners can contact Mercedes-Benz Customer Service at 1-877-496-3691.…

Fuel System, Gasoline:delivery:fuel Pump NHTSA Campaign #23V445000 · manufacturer #2023070012 · 26/06/2023

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.

Fix: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.

Structure:frame And Members NHTSA Campaign #23V200000 · manufacturer #2023040009 · 24/03/2023

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 Maybach S580 and S580 vehicles. The bulkhead that separates the engine compartment from the passenger compartment may not have been properly sealed, causing water to drain into the passenger compartment. Water intrusion into the foot wells may cause corrosion and/or short circuits to electrical components, disabling safety features, including seat belt tighten…

Fix: Dealers will repair the bulkhead front wall sealing, free of charge. Owner notification letters were mailed May 12, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023040009.

Visibility:fixed Panaramic Roof/sky Light Assembly NHTSA Campaign #23V098000 · manufacturer #2023020008 · 17/02/2023

Mercedes-Benz USA, LLC (MBUSA) is recalling one 2021 S 580 4Matic vehicle. The fixed front glass panel between the windshield and the panoramic sunroof may not be properly secured and may detach.

Fix: Dealers will replace the front fixed glass panel, free of charge. The owner notification letters were mailed March 17, 2023. The owner may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023020008.

Back Over Prevention:display Function NHTSA Campaign #22V493000 · manufacturer #2022080002 · 11/07/2022

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 AMG EQS53, EQS580, EQS450, 2021 S500, S580, and Maybach S580 vehicles. The rearview camera may not display the rearview image due to a software error in the MBUX multimedia system. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 111, "Rear Visibility."

Fix: Dealers will update the MBUX multimedia system software, free of charge. Owner notification letters are expected to be mailed August 19, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022080002.

Communication: Auto Crash Notification NHTSA Campaign #22V365000 · manufacturer #See Recall Schedule · 20/05/2022

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling…

Fix: The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owne…

Steering:column NHTSA Campaign #22V214000 · manufacturer #2022040006 · 01/04/2022

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 S580 4Matic and S500 4Matic vehicles. The electrical connector to the steering column module may not be secured properly, which can disable gear shifts and/or safety features including the electronic stability program, the driver's air bag, and turn signal indicators.

Fix: Dealers will inspect and reinstall the cover for the electrical connector, as necessary, free of charge. Owner notification letters were mailed May 13, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040006.

Steering: Steering Wheel/handle Bar NHTSA Campaign #22V189000 · manufacturer #2022040010 · 25/03/2022

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.

Fix: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.

Exterior Lighting:hazard Flashing Warning Lights NHTSA Campaign #22V167000 · manufacturer #2022040013 · 18/03/2022

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 EQS 450, EQS 580, and 2021 S500 and S580 vehicles. A software error may disable the rear turn signals, hazard lights, and reverse lights.

Fix: Dealers will update the rear signal software, free of charge. Owner notification letters were mailed May 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040013.

Air Bags:critical Fasteners NHTSA Campaign #22V124000 · manufacturer #2022030024 · 04/03/2022

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 S580 4Matic vehicles. The air bag control unit may be improperly secured and may result in an unintentional air bag or seat belt deployment, or an improper deployment in the event of a crash.

Fix: Dealers will inspect and tighten the air bag control unit fastening nuts, as necessary, free of charge. Owner notification letters were mailed April 15, 2022. Owners may contact MBUSA customer service at 1-800-637-6372. MBUSA's number for this recall is 2022030024.

Source: U.S. NHTSA, checked 8 Oct 2026. A campaign covers the model year; to see whether a particular car still needs the repair, check its VIN on NHTSA.gov or ask a franchised dealer.

2021 Mercedes-benz S 580 MPG & running costs

Combined19–20 mpg
City17 mpg
Highway25 mpg
Est. annual fuel cost$4,225
EPA size classLarge Cars
TransmissionAutomatic 9-spd
Forced inductionTurbocharged
Engine start-stopYes
Passenger volume118 cu ft
Cargo volume14 cu ft
5-yr fuel cost vs average new car$9,125 more

Source: U.S. EPA / DOE fueleconomy.gov. The EPA lists 2 versions of this model year; combined is shown as a range and the other figures are averages.

Estimated 5-year cost to own

A rough guide to what running a 2021 Mercedes-benz S 580 costs over five years and 75,000 miles.

Fuel (5 yrs)$21,125
Fuel only$21,125
Per mile$0.28

How this is estimated: fuel is the U.S. EPA annual cost at 15,000 miles a year. There aren't enough comparable listings to estimate depreciation for this model, so it is left out. Not included: insurance, maintenance, repairs, taxes, registration and finance costs. Treat it as a comparison guide, not a quote.

2021 Mercedes-benz S 580 vehicles on record

Other Mercedes-benz S 580 model years

2021 Mercedes-benz S 580 — frequently asked questions

Does the 2021 Mercedes-benz S 580 have any safety recalls?

NHTSA lists 16 recall campaigns for the 2021 Mercedes-benz S 580. Whether an individual car still needs a recall repair depends on its VIN — check it on NHTSA.gov or ask a franchised dealer. Recall repairs are done at no charge.

What gas mileage does the 2021 Mercedes-benz S 580 get?

The 2021 Mercedes-benz S 580 has U.S. EPA estimates of 19–20 mpg combined, depending on engine and trim (2 versions).

Sources: NHTSA (recalls, complaints, crash tests), U.S. EPA (fuel economy). Vehicle data only — CarLogs never shows owner information.